International Chemical Safety Cards

2-(ACETYLOXY)BENZOIC ACID ICSC: 0822
2-(ACETYLOXY)BENZOIC ACID
Acetylsalicylic acid
2-Acetoxybenzoic acid
Aspirin
C9H8O4 / CH3COOC6H4COOH
Molecular mass: 180.2
CAS # 50-78-2
RTECS # VO0700000
ICSC # 0822
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

  • INHALATION
    		• Cough. Sore throat.
    		Ventilation (not if powder).
    		Fresh air, rest. Refer for medical attention.
  • SKIN
    		• Redness.
    		Protective gloves.
    		Rinse skin with plenty of water or shower. Refer for medical attention.
  • EYES
    		• Redness. Pain.
    		Safety goggles.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• Nausea. Vomiting.
    		Do not eat, drink, or smoke during work.
    		Rinse mouth. Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place (extra personal protection: P2 filter respirator for harmful particles).
    		Well closed.

    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0822 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

    International Chemical Safety Cards

    2-(ACETYLOXY)BENZOIC ACID ICSC: 0822

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    PHYSICAL STATE; APPEARANCE:
     COLOURLESS TO WHITE CRYSTALS OR WHITE CRYSTALLINE POWDER , WITH CHARACTERISTIC ODOUR.

    PHYSICAL DANGERS:
     Dust explosion possible if in powder or granular form, mixed with air.

    CHEMICAL DANGERS:
     The solution in water is a weak acid.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
     TLV: 5 mg/m3 (ACGIH 1997).
    MAK not established.


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation and by ingestion.

    INHALATION RISK:
     Evaporation at 20░C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance irritates the eyes, the skin, and the respiratory tract. The substance may cause effects on the blood and central nervous system, if ingested in large amounts.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
     Animal tests show that this substance possibly causes toxic effects upon human reproduction.
    PHYSICAL
    PROPERTIES
    Decomposes below boiling point at 140░C
    Melting point: 135░C
    Density: 1.4 g/cm3
    Solubility in water, g/100 ml at 25░C: 0.33
    		 Solubility in water: poor (0.25 g/100 ml at 15░C)
    Vapour pressure, Pa at 25░C: about 0.004
    Octanol/water partition coefficient as log Pow: 1.19
    ENVIRONMENTAL
    DATA
    N O T E S
    Acenterine, Acesal, Acetol, Acetophen, Acetosal, Acetosalin, Acetylin, Acetylsal, Acisal, Acylpyrin, Asagran, Aspro, Asteric, Caprin, Duramax, Ecotrin, Empirin, Neuronika, Polopiryna, Rhodine, Salacetin, Xaxa are trade names.
    Transport Emergency Card: TEC (R)-61G12c
    ADDITIONAL INFORMATION


    ICSC: 0822 2-(ACETYLOXY)BENZOIC ACID
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.